> > I am very interested knowing about a neuro subscribing rilutek(a new med. > that is supposed to slow the disease process of Lou Gehrings disease, but > that, being a glutamate-antagonist, can be expected on theoretical grounds > to be effective against leva-dopa induced dyskinesia of PWP's too. I wrote > about a week ago something about dextrometorphan, which is a > glutamate-antagonist, and an ingredient of an over the counter cough syrop > (Darolan in Holland). In the UK it is sold under the trade name Benylin, Dry Coughs . I tried it for end of dose dyskinesia . There was a considerable reduction in strength and duration of dyskinesia . I am not using it on a regular basis because the dextromethorphan hydrobromide contains bromide . This bromide may be detrimental to PD ( possibly ) Thanks for the info . Any further info would be much appreciated . > I was pointed on that as a reaction on my question about a possible similarity > between the physiological process that causes leva-dopa induced dyskinesia > especially the interdose- or wearing off kind and cold turkey symptoms of > drug addicts. They are also supposed to be diminished by anti-glutamates. I > got an atricle in print, and no scanner, from CNS drugs, juni 1998,blz. 421 > -429 Glutamate Antagonists for Parkinson's Disease, Rationale for Use and > Therapeutic Implications Alison J Cooper, Camille B. Carroll, and Ian J > Mitschell. > If someone is interested and can't procure it from Pubmed, I'll type and > send the summary. > Debbie, I am very interested to know the rationale of your mothers doc > subscribing it, and if he has done so before to other patients and what are > the results. But probably you will be able only to tell about the results > of this meds for your mother and that will be interesting for me too. Let's > hope for the best for your mother in the first place, > Ida > > -------------------------------------------------------------- > Vriendelijke Groeten / Kind regards, > > Ida Kamphuis mailto: [log in to unmask] > > peace Alastair ( [log in to unmask] )