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A while ago someone asked about Reglan . It is one of the drugs which helps the digestive system work better but as it does it worsens the Parkinson symptoms. There are a number of other drugs which should be avoided by PWP and a list was posted recently and can be found in the archives. While in the archives looking for this list you could take a look at the articles about a drug called cisapride. (it promotes stomach emptying and an active intestine.) I found three med journal references to its use in Parkinsons. Cisapride is different from the other gastro-intestinal (GI) drugs in that it can't pass the blood-brain barrier and therefore can't mess up the dopamine balances in the brain. Like everything we take for Parkinsons, cisapride is a powerful drug and must be treated with great caution. My doctor says NO BOOZE!! Not a drop! No beer! No wine! How long must you stay on the water wagon? As long as you are taking cisapride. I am not recommending that anyone try this drug. Your neurologist and GI specialist know you and your pharmacist knows all the drugs you take. Please consult them. Anne Rutherford <[log in to unmask]>