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The older the father the greater the Alzheimer's risk, study says

LONDON (September 16, 1998 1:43 p.m. EDT http://www.nandotimes.com) - A fa=
ther
who waits to have children may be increasing their chance of developing
Alzheimer's disease, New Scientist magazine said on Wednesday.

Researchers in Germany suspect that DNA damage that builds up with age can=
 be
passed on from older fathers to their children which could raise their cha=
nces
of developing the progressive degenerative brain disorder.

"There is an accumulation of environmental factors which somehow alter the
genome of the father," Lars Bertram, of the Technical University of Munich=
,
told the magazine.

He and his colleagues studied 206 people with Alzheimer's disease and
discovered that patients who were least likely to have an inherited risk h=
ad
fathers who were older than those of the higher genetic risk group or heal=
thy
people.

Fathers of sufferers in the low genetic-probability group had been 35 to 3=
7
years old when their child was born, while fathers in the high genetic ris=
k
group were four to six years younger when they became a parent.

Alzheimer's disease is the most common form of dementia, affecting about 1=
0
million people worldwide. It causes loss of memory, changes in personality=
 and
affects a person's ability to think. Drugs can slow the progression of the
disease but there is no cure.

The disease is not completely understood but researchers suspect a buildup=
 of
plaque in the brains of sufferers causes problems in the brain's communica=
tion
system.
=1A
Copyright =A9 1998 Nando.net
Copyright =A9 1998 Reuters News Service

janet paterson - 51/10 - almonte/ontario/canada
http://www.newcountry.nu/pd/members/janet/
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