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Good morning Patricia,
In a 4 year period from 1993-1997 i had 5 back surgerys and a
pallidotomy. When I was on anything that seemed related to helping my back,
it brought on a reduction in the effectiveness of my sinemet(I am taking 7-8
siunemet 50/200cr every 24 hrs.) It seemed to apply particularly to any kind
of steroid.
hope this helps--take care-----pete