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Why the books (and most neuros) say to avoid Eldepryl late in the day: It breaks down into amphetamine and methamphetamine, powerful stimulants known to the illegal drug crowd as "speed". Why apomorphine tastes bad and makes you sick: It was originally developed as an emetic for cases of poisoning in children and small animals. But it's also a powerful and fast-acting dopamine agonist, useful in clinical studies and (where prescription is approved) as a "rescue" measure for PD patients who suffer unpredictable severe "off" periods. Nausea is avoided if it's given by injection or by nasal spray. As a peculiar side effect, it occasionally induces pathological excessive libido in male recipients. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013