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Ann Gibbons CG Joe 64/1.5 wrote in part: >Do you think that his skewed sleep pattern could be due to the Mirapex? my opinion (non-professional) is that it is certainly possible. the probability might be answered by your selves if your memory suffices to answer whether Joe got any improvement in symptoms reduction after working up to half or less the 2.5 mg per day dosage. >Does Requip have the same sleep side-effects? you have made a conclusion that Mirapex has specific sleep side effects! based upon one sample. >and we would like to have a possible alternative med to Mirapex. I suggest that maybe the med is not the cause of the sleep pattern. the two drugs have somewhat different D1, D2, D3, site effects- so would be likely to differ. my age is 62. Joe is not a young onset pwp and I have taken carbidopa/levodopa for 14 years. i added Mirapex last year when i could get it. i used it sparingly and went from 0.75 mg per day to four 0.25 tabs per day two months ago. it has a 7 to 9 hour half life so i try to take at 6-hour intervals: arising, noon, 6 PM, and just before retiring. Perhaps the alternative is to take less Mirapex. i also take half an Eldepryl generic substitute each day instead of 5 mg every other day. Joe, are you feeling spunky most of the time? do you have some goals and projects that interest you and occupy your body and mind - giving you mental and physical exercise? take care love your self love your others this is living giving is living the above is my answer to Piet Hein's grook i'd like to know what this whole show is all about before it's out ron Ronald Vetter 1936, dz PD 1984, carbidopa/levodopa, Mirapex, selegiline [log in to unmask] Ridgecrest, California http://www.ridgecrest.ca.us/~rfvetter