This is a multi-part message in MIME format. ------=_NextPart_000_0018_01BDEA51.77E52B40 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable There have been a few negative comments on apomorphine in the last = couple of days. I have carry no brief for the stuff but there was an = article a few months ago in the BMJ (British Medical Journal) which = suggested that it was underused in the treatment of PD. I forget the = details but I believe it usually used to help with on/off problems.=20 Two comments I noted in particular. One reported that they had taken it orally and had been sick as a = result. I understood that you normally inject it and that you had to = take domperidone initially to prevent the sickness. The other was from Nigel who had been put off it because the 3 PWPs he = had seen who were on it seemed to be suffering from worse dyskinesias = than those that weren't. But maybe they were taking apomorphine because = of their dyskinesias rather than the other way round Jamie 47/10 ------=_NextPart_000_0018_01BDEA51.77E52B40 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable <!DOCTYPE HTML PUBLIC "-//W3C//DTD W3 HTML//EN"> <HTML> <HEAD> <META content=3Dtext/html;charset=3Diso-8859-1 = http-equiv=3DContent-Type> <META content=3D'"MSHTML 4.72.3110.7"' name=3DGENERATOR> </HEAD> <BODY bgColor=3D#ffffff> <DIV><FONT face=3DArial> <P>There have been a few negative comments on apomorphine in the last = couple of=20 days. I have carry no brief for the stuff but there was an article a few = months=20 ago in the BMJ (British Medical Journal) which suggested that it was = underused=20 in the treatment of PD. I forget the details but I believe it usually = used to=20 help with on/off problems. </P> <P>Two comments I noted in particular.</P> <P>One reported that they had taken it orally and had been sick as a = result. I=20 understood that you normally inject it and that you had to take = domperidone=20 initially to prevent the sickness.</P> <P>The other was from Nigel who had been put off it because the 3 PWPs = he had=20 seen who were on it seemed to be suffering from worse dyskinesias = than=20 those that weren't. But maybe they were taking apomorphine because of = their=20 dyskinesias rather than the other way round</P> <P>Jamie 47/10</P> <P> </P></FONT></DIV></BODY></HTML> ------=_NextPart_000_0018_01BDEA51.77E52B40--