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Hello Coleen, Nigel and Delda,

Sat, 26 Sep 1998 21:24:17 -0700 Coleen Pettit <[log in to unmask]> wrote:

<<<<  eldypryl keeps you up at nite if you take it after 12 noon?  >>>>

H:      Yes!

AND

Sat, 26 Sep 1998 21:27:29 -0700 Coleen Pettit <[log in to unmask]> wrote:

<<<<  also, are you saying that eldypryl wears off and mid morning you get
tired? that is what happens to my hubby...69/2? he gets going in the morning
and then poops out around 10:00am and doesn't understand why...we always
thought it was just parkinsons....it is the lack of eldypryl??  >>>>

H:      Probably the lack of sleep at night.

AND

Sat, 26 Sep 1998 21:36:09 -0700 Coleen Pettit <[log in to unmask]> wrote:

<<<<  I also note from your message that you take Eldepryl at midday, this
goes against what my Neuro' told me, and my own experience, which is that it
should only be taken in the morning as it can cause sleeplessness if taken
later. I have a question...didn't your neurologist give you the perscription
of eldypryl to take twice a day...morning and evening? Bob was told to take
his at those times adn he does have lack of sleep sometimes..early in the
morning...he says he is just not tired..maybe that is the problem?? jeesh,,
why would the DR tell us to do this and this could be the sleeping problem?
>>>>

H:      Eldepryl can cause sleepingproblems. To prevent that the second pill
        must be taken at or before noon. If you take two pills a day you can
        take one pill in the morning and one at noon. Are you still having
        sleepingproblems, you can (after consulting your neuro) take both
        pills at the same time in the morning. Still having sleepingproblems
        you can reduce (after consulting your neuro) the dose to one pill in
        the morning. Still not sleeping well you could (a.c.y.n.) consider
        to stop taking Eldepryl. Also keep in mind that sleeplessness can
        also be caused by other anti-PD-meds!!

AND

Sun, 27 Sep 1998 08:28:16 Nigel Harland <[log in to unmask]> wrote:

<<<<  No, my neurologist was quite clear on the times when to take Eldepryl,
that is to say once a day, in the morning, preferably shortly after you get
up, as the later in the day that you take it, the higher is the risk that
you will experience sleeplessness.Despite taking his advice, I still
suffered from some difficulty getting to sleep, and when I actually achieved
sleep, it was a very light sleep full of wacky almost hallucinatory dreams,
too weird to put into print, this was definitely down to the eldepryl, as it
only started happening after it was prescribed. When I mentioned this to my
neuro' he prescribed the anti depressant Amitryptiline, after which I began
sleeping well at night with more or less normal dreams.You may well ask why
did I continue with the eldepryl, the answer being that despite the
sleepless nights it did a good job in " smoothing out" the intake and
prolonging the benefit of  Madopar (Sinemet equivalent).  >>>>

H:      Eldepryl makes the working of the Madopar stronger, and this may be
        probably the cause of the "hallucinatory" dreams. Suggestion:
        instead of taking the Amitriptyline, you might try to take less
        Madopar (of course a.c.y.n. = after consulting your neuro).

AND

Sun, 27 Sep 1998 08:42:22 EDT Delda White <[log in to unmask]> wrote:

<<<<  My husband's neuro was also very clear -- twice a day, once in
morning, once at noon.  Several List members have confirmed this in the
months I have been on the List -- i.e., do not take eldepryl after noon
because it will cause sleeplessness, but taking it at noon is fine.  >>>>

H:      You are correct! Also see my earlier comment above!!

Hope this helps,  Hans.