<fontfamily><param>Arial</param>Apomorphine Apomorphine has been always more used in Europe than in the US. That is in part because the anti-emetic and anti nausia med. domperidone is an accepted med. in Europe ( I am not sure if this holds for all European countries.) and is always prescribed together with apomorphine. Domperidone is not admitted in the USA. Apomorphine is for most neuro's a last resort, which can be used when nothing else is helpfull any more. It controls for some patients effectively "wearing off" dyskinesia. I once did see a woman with heavy dykinesia using it. The effect of an apomorphine injection seemed me to be a miracle Within a few minutes the dyskinesia had disapeared completely. But the time this effect could keep was about 30 min. It was supposed that after these 30minutes the sinemet would take over the job. My impression was that it is more a rescue drug, than a drug that could take over the task of sinemet. But as such it might be usefull. When apomorphine is used as replacement of sinemet ,administered by a pump, the results can be miraculous too, but mostly don't hold . Regards Ida </fontfamily> -------------------------------------------------------------- Vriendelijke Groeten / Kind regards, Ida Kamphuis mailto: [log in to unmask]