> From: [log in to unmask] > Subject: NADH > About a year ago, much was written about NADH. Is anyone still using it? > What kinds of results have you had? > > Hi I have been for the last five months or so trying to evaluate the beneficial effects of energy boosting food supplements on my PD . These substances are NADH .CoQ10 and lipoic acid . The trouble I have found is trying to devise an experiment that would show energy levels . Repeatability is the hallmark of a scientific experiment . Because my energy level varies so much with my PD it does not provide a level surface from which to measure the effects of the energy boosting substances . When I am " on " I have more energy than when " off "and dyskinesia is the worst state for energy . Even within these states there is great variation . I used to think that L-dopa kept me alert but of late I find that I have great difficulty keeping my eyes open during the day when I am " on " with the L-dopa . Because of these difficulties I have not come to any definitive conclusion except that PD is not in my view not a mitochondrial dysfunction . If PD were caused by the inefficiency of the cells to produce energy then I feel that these energy boosting substances would have a much more obvious effect . Ther are many suppliers on the web . I have tried two different makes of NADH, two different makes of Lipoic acidand so far only one CoQ10 . I have found little quantifiable effect from any of these ( this of course could be due to my particular PD ) This experiment is not crucial to PD so it is on the back burner( in my view). I am currently engaged in setting up an experment to assess the viral -PD connection . This will involve travelling to Mexico where medicinal drugs are more easily obtainable . Conclusion In my view the lack of energy is not central to PD . So if one can cure whatever is causing PD then energy levels would return to normal .The use of energy boosting substances like NADH is marginal in the treatment of PD . peace Alastair ( [log in to unmask] )