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We are trying to get in touch with my mother's doctor. She is on a weekend vacation (some vacation) and she has terrible internal and external tremors (she usually doesn't have an external tremor) and both eyes are bloodshot, very off balance (something she hasn't felt for awhile now) and she feels lousy (know this is general, but that's how she put it). She is on Sinemet and Requip and recently started Artane and Rilutek (the latter for ALS). She thinks it's a drug reaction. We suspect the Rilutek but it's possible it's the Artane (or a combination). Has anyone on Artane had similar reaction?? Thanks. Debbie White [log in to unmask]