My wife (age 65, PD for 3 yrs, on Atamet 25/100 4 x daily, estrogen/progesterone, multivitamins, calcium, magnesium, E, C ) - is awakened early each morning with intestinal gas & cramps that disturbs her sleep. Eating a cracker sometimes helps and she rarely has the problem during the day. Constipation occurs frequently, but relieving it doesn't solve the problem. Efforts to diagnose & eliminate this problem by selectively discontinuing the hormones, vitamins and decreasing Atamet to 3x daily did not help. Our doctor doesn't think the gas is related to her medicines or to the PD. Has anyone on the List had similar problems with gas? Any suggestions? Thanks, Ralph