Wed, 7 Oct 1998 00:36:58 -0400 judith richards <[log in to unmask]> wrote: <<< I have been taking one Amitriptyline (25mg) at bedtime for almost two years, and have had no trouble at all. It was prescribed as a mild antidepressant and a sleep aid. The psychiatrist who prescribed it was also trained in neurology and is very knowledgeable about Parkinsons. >>> Hi Judith, I'm not saying Amitriptyline should not be prescribed for PWP, because I'm sure it will work fine for many PWP (as for you). What I intended to argument, was that, even when you have a very good specialist, you always have to stay very alert about your meds, because even meds AGAINST a symptom, can IN SOME PATIENTS make a symptom worse instead of help against it! BTW: Did you know that Amitriptyline can have influence on the (side-)effects of Levodopa, and vice versa? Hans.