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Hilary, are you taking whole 25/100 Sinemet tablets? if you have never tried halves at 2-hour intervals, you might find less dyskinesia. Ronald Vetter 1936, dz PD 1984, carbidopa/levodopa, Mirapex, selegiline [log in to unmask] Ridgecrest, California http://www.ridgecrest.ca.us/~rfvetter