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I think I mnetioned somewhere that I take halves of 25/100 sinemet CR at 1.5 to 2 hour intervals - for that very reason. ie, during the day. At night I take every 3 to 4 hours. Hilary Blue ------------------------------------------------------------------------------------------------------------ Ronald F. Vetter wrote: > > Hilary, are you taking whole 25/100 Sinemet tablets? > > if you have never tried halves at 2-hour intervals, you might find less > dyskinesia. > > Ronald Vetter 1936, dz PD 1984, carbidopa/levodopa, Mirapex, selegiline > [log in to unmask] Ridgecrest, California > http://www.ridgecrest.ca.us/~rfvetter