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From:   William T.Wallace Jr.[SMTP:[log in to unmask]]
Sinemet

I am a new observer /reader of your PD network. I am a parkinsonian, =
diagnosed in 1986.  I am 63 years old and retired from state public =
health
positions last year.
        I am interested in the discussions about Sinemet use at night. I =
attempt to maintain a 24 hour level of dopamine and Permax. I use both =
the Sinemet CR - 25/100 q4h.The Permax I also take q4h I have spent long =
hours attempting to maintain a perfect balance (impossible as you know). =
    If that is not enough, I supplement with short acting Sinemet. All =
this works quite well for me.My goal is to prevent  leg cramps which =
plagued me for a couple of years. It seems to work. It never keeps me =
awake. I am asleep shortly after my head hits the pillow. I will attempt =
to answer any questions
                                        William T. Wallace MD, MPH