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Hi Marianne and all--recently I have had to dangle my feet sitting on the bed before I can bear weight on my feet. Don't take Sinemet CR. Do take Mirapex. But I think this has been since starting Tasmar. Barbara Blake-Krebs 58/14 [log in to unmask] << Hello William and Pete I have had Parkinson 15 years and also take Sinemet Cr., regular Sinemet, Amantadine and Mirapex. I wake up in the morning, not having any problems moving but all knotted up in my loweer back and have trouble putting any weight on my feet. It is like cramps. Has anybody heard that Sinemet Cr. causes pain of any kind? Marianne Rome >>