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Howard wrote in part > I a just started my second step if Tasmar. > After 20 hours of being awake and 6 hours being in an agitated >state I was able to get a few hours sleep. The agitated state is torture. have you reduced your Sinemet dosage? the Tasmar is making the levodopa level higher in the blood. ask or tell the doctor that you need to reduce the Sinemet about 40%. Ronald Vetter 1936, dz PD 1984, carbidopa/levodopa, Mirapex, selegiline [log in to unmask] Ridgecrest, California http://www.ridgecrest.ca.us/~rfvetter