Hello Everyone: I have a friend who has tried Tolcapone, it has been helpful to reduce Sinemet, however, it causes nausea and feeling flu like. Is this something that passes or are there ways to take Tolcapone with anything else to reduce unwanted side effects. The amount taken is just 100 mg three times daily. Would appreciate any advice or experiences. Thanks.........Nigel ------------------------------------------------- Nigel Cockle 59 Norley Road, Cuddington, Northwich, Cheshire. CW8 2JY England Tel +44 1606 882150 Email [log in to unmask] -------------------------------------------------