In a message dated 1998/10/31 00:59:02, you write: << The usual is 5 mg at breakfast, 5 mg at lunch. Some say that Eldepryl should not be taken much after noon if sleep is a problem. I personally find this strange since the medication has a very long half-life. The stuff is still measurable in significant amounts ten days after the most recent dose. >> hi will i believe that the half-life in the brain is very short while the half-life in the blood is much longer there was quite a detailed discussion on this some time ago - it should be in the archives janet