This is a multi-part message in MIME format. ------=_NextPart_000_0008_01BE126C.BCF6A040 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable In response to Ervin's query: I am 62 and have had PD for three years. = So far it has been well-controlled with Eldepryl (Seligiline), Symmetrel = (Amantadine) and Mirapex. Each case of PD is different, but in the last = couple of years many specialists in Parkinsons have begun using dopamine = agonists like Mirapex as the first approach to early PD, especially in = people under sixty. This is because Sinemet, long the gold standard, = often seems to carry with it problematic side effects after 3-5 years. = Delaying its use, therefore, by using other medications, delays those = potential side effects. Just yesterday I attended a lecture by a leading West Coast Parkinsons' = specialist. She strongly supported the approach described above, but = said that unfortunately, many neurologists throughout the U.S. still = prescribe Sinemet as the first Parkinsons medication -- no matter what = the circumstance. ------=_NextPart_000_0008_01BE126C.BCF6A040 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable <!DOCTYPE HTML PUBLIC "-//W3C//DTD W3 HTML//EN"> <HTML> <HEAD> <META content=3Dtext/html;charset=3Diso-8859-1 = http-equiv=3DContent-Type> <META content=3D'"MSHTML 4.71.1712.3"' name=3DGENERATOR> </HEAD> <BODY bgColor=3D#ffffff> <DIV><FONT color=3D#000000><FONT size=3D3>In response to Ervin's = query: I am=20 62 and have had PD for three years. So far it has been = well-controlled=20 with Eldepryl (Seligiline), Symmetrel (Amantadine) and Mirapex. = Each case=20 of PD is different, but in the last couple of years many specialists in=20 Parkinsons have begun using dopamine agonists like Mirapex as the first = approach=20 to early PD, especially in people under sixty. This is because = Sinemet,=20 long the gold standard, often seems to carry with it problematic side = effects=20 after 3-5 years. Delaying its use, therefore, by using other = medications,=20 delays those potential side effects.</FONT></FONT><FONT=20 size=3D3></FONT> </DIV> <DIV><FONT color=3D#000000><FONT size=3D3></FONT></FONT><FONT=20 size=3D3></FONT> </DIV> <DIV><FONT face=3D"" size=3D3>Just yesterday I attended a lecture by a = leading West=20 Coast Parkinsons' specialist. She strongly supported the approach=20 described above, but said that unfortunately, many neurologists = throughout the=20 U.S. still prescribe Sinemet as the first Parkinsons medication -- = no=20 matter what the circumstance.</FONT></DIV></BODY></HTML> ------=_NextPart_000_0008_01BE126C.BCF6A040--