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--------------2A88805C16BD697AD31C4F0C Content-Type: text/plain; charset=us-ascii Content-Transfer-Encoding: 7bit Hello all , Zunin wrote: > In response to Ervin's query: I am 62 and have had PD for three > years. So far it has been well-controlled with Eldepryl (Seligiline), > Symmetrel (Amantadine) and Mirapex. Each case of PD is different, but > in the last couple of years many specialists in Parkinsons have begun > using dopamine agonists like Mirapex as the first approach to early > PD, especially in people under sixty. This is because Sinemet, long > the gold standard, often seems to carry with it problematic side > effects after 3-5 years. Delaying its use, therefore, by using other > medications, delays those potential side effects. Just yesterday I > attended a lecture by a leading West Coast Parkinsons' specialist. > She strongly supported the approach described above, but said that > unfortunately, many neurologists throughout the U.S. still prescribe > Sinemet as the first Parkinsons medication -- no matter what the > circumstance. This seems to me to be still a controversial issue . Perhaps Brian (from UK) that is a long time user of Sinemet ( Madopar ) can give us his view about it . Regards , +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+ --------------2A88805C16BD697AD31C4F0C Content-Type: text/html; charset=us-ascii Content-Transfer-Encoding: 7bit <!doctype html public "-//w3c//dtd html 4.0 transitional//en"> <html> <body bgcolor="#FFFFFF"> Hello all , <p>Zunin wrote: <blockquote TYPE=CITE><font color="#000000"><font size=+0>In response to Ervin's query: I am 62 and have had PD for three years. So far it has been well-controlled with Eldepryl (Seligiline), Symmetrel (Amantadine) and Mirapex. Each case of PD is different, but in the last couple of years many specialists in Parkinsons have begun using dopamine agonists like Mirapex as the first approach to early PD, especially in people under sixty. This is because Sinemet, long the gold standard, often seems to carry with it problematic side effects after 3-5 years. Delaying its use, therefore, by using other medications, delays those potential side effects.</font></font> <font face=""><font size=+0>Just yesterday I attended a lecture by a leading West Coast Parkinsons' specialist. She strongly supported the approach described above, but said that unfortunately, many neurologists throughout the U.S. still prescribe Sinemet as the first Parkinsons medication -- no matter what the circumstance.</font></font></blockquote> <p><br>This seems to me to be still a controversial issue . Perhaps Brian (from UK) that is a long time user of Sinemet ( Madopar ) can give us his view about it . <p>Regards , <p> +----| Joao Paulo de Carvalho |------ + <br> | [log in to unmask] | <br> +--------| Salvador-Bahia-Brazil |------+ <br> </body> </html> --------------2A88805C16BD697AD31C4F0C--