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Since I seem to have reached that stage in PD where it has become increasingly difficult to walk the narrow line between too little and too much levodopa and to achieve that delicate balance between PD symptoms on the one hand and drug-induced dyskinesia on the other, I'm wondering to what degree food intake is a factor. Is my difficulty in finding just the right drug dose a result of not paying enough attention to what did I eat and when did I eat it? I know about the desirability of maintaining that nice 1/7 ratio of protein to other nutrients, although I haven't tried to observe this rule consistently. Are there other factors that can be important, such as the quantity of food eaten, the time drugs are taken vs. time of eating, the frequency of food intake, ratio of solids to liquids, the effects of regularity and of constipation (and its opposite), the digestibility of what I ate -- things of that order? Will I have to become really disciplined about food, and in the end eat the same things every day at the same time and in the same quantity in order to achieve the right drug effective doses? When I pig out, do I in effect cast my pills before swine? I would greatly appreciate any observations, good rules of thumb or sources of information on this subject. Phil Tompkins Hoboken NJ age 60/dx 1990