Good morning Phil: >>> Phil Tompkins <[log in to unmask]> 11/19/98 10:22am >>> >>>>Since I seem to have reached that stage in PD where it has become increasingly difficult to walk the narrow line between too little and too much levodopa and to achieve that delicate balance between PD symptoms on the one hand and drug-induced dyskinesia on the other, I'm wondering to what degree food intake is a factor.<<<<< * * * * Phil- There was a recent study (reported in the "Parkinson's Disease Update" - #93) that measured food intake against SinemetCR efficacy and absorption. The conclusion was - the time of meal ingestion is important to the quality of levodopa absorption. The recommendation was to take the CR 30 minutes BEFORE meals for best benefit. If you would like a copy of the reprot summary - e-mail me your street address. Stephan 54/8