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Kathryn Holden, Kathryn, My friend Anne, who does not hve direct access to a computer has asked me to pose this question. Her neurologist recommended her to take 150 mg per day of vit B6, for what he diagnosed as carpal tunnel syndrome. THis was on Cot 14. Since then, her physical condition has deteriorated; her eyelids are drooping, she has difficulty swallowing, her bladder and vocal chords are also affected - she has almost lost her voice. And the 'carpal tunnel syndrome' has got worse and spread to her elbows. She has doubled her sinemet, and when she saws him yesterday, he told her to put up the dosage once again. She surmises that the B6 is probably to blame - is she correct? She has stopped taking it,but she wonders if the damage is permanent. and how long it will take her body to get rid of it? She plans to seek another neurologist. By the way, she does not have regular PD but a condition described as 'dopamine-responsive dystonia" . Any comments? Hilary Blue