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I have a printed write-up on the horrors of Premarin production. Anyone who would want a copy can e-mail me privately to exchange snail mail addresses off list. There are many very effective synthetically produced ERT's available. According to the write-up I have, a few are: Estradiol Transdermal System, Estradiol tablets, Estropipate, Estrone and Estrace Joan Cutchins [log in to unmask] P.S. I apologize for being late answering this thread, I haven't logged on for a few days.