Hi all, This is a duplicate of what I sent yesterday - not sure if it was in fact sent. -----Original Message----- From: Kleynscheldt, Gerrit Sent: Tuesday, January 05, 1999 11:07 AM To: 'janet paterson'; Multiple recipients of list PARKINSN Subject: Mouth Spray Hi all, Someone wrote recently about the advantages for a PWP to use Vitamin C. Quote: "I was having problems before I started the vitamins. In fact I believe right now some of Gods greatest gifts to PWP are the Internet and Vitamin C. Of course there is also loving family, good friends and knowledgable and caring doctors when you can find one." It seems as if the usage of Vitamin C speeds up the effective absorption of the PD-drugs. I have recently been introduced to KareMor International Inc. They specialise in oral absorption products. According to their advertised material the absorption rate of a tablet/pill is around 10% in up to 4 hours. Their patented oral spray gets absorbed directly through the lining of the mouth (buccal mucosa) at a rate of 95% in 30 seconds. The digestive tract is bypassed in the process. Although their current products do include a Vitamin C spray, amongst others, the fact that the digestive tract is bypassed with the spray means that the tablets/pills used by the PWP will not be absorbed faster if a Vitamin C spray is used. (unless you can SPRAY the pills right through the lining of the mouth...) This got me thinking. (dangerous this). Should we not attempt/try/fight/etc to get some (a lot, actually) research going into having the various Parkie-medications made available in the form of oral sprays? This would mean - if all the statements are correct - that OFF-times & waiting for medication to "kick in" will be reduced, no struggle with big tablets and small throat openings, swallowing problems, etc. I have spoken to the doctor who heads KareMor in South Africa. He has difficulty getting authorisation from our Government to go heavier and deeper into medication. He is involved, however, at Grootte Schuur Hospital with research into the uses of admitting medication through oral spray for transplant patients and Aids patients. The thinking process there seems to be that medication is creating havoc in the digestive system for these patients and that nutrients could be admitted by the patient through the use of an oral spray (or vica versa). The current product range of KareMor includes products for Nutrition, Vitamins, Arthritics, Smoke-ending, Stress related, Heart-smart, PMS, Prenatal, Herbal products, Mild depression, Insomnia problems, Dietary, Paracetamols for headaches etc. (According to this doctor the tablet & pill making industry has invested very heavily into their machinery and they will fight tooth & nail to not lose market share. I believe that this is not our problem.) Does anybody have any more information about this? KareMor International Inc. has a very comprehensive web site at: http://www.karemor.com <http://www.karemor.com> Regards, Gerrit Kleynscheldt (44,39) Tel: +27 21 947 8918 (Local 021 947 8918) Fax: +27 21 947 1521 (Local 021 947 1521) Please note the following: Because e-mail can be altered electronically, the integrity of this communication cannot be guaranteed.