This is a multi-part message in MIME format. ------=_NextPart_000_0212_01BE3B49.799C7260 Content-Type: text/plain; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable I am taking Sinemet, Sinemet CR, Mirapex, clonzepam, and amitriptyline = for my PD. I also take Ultram for an anti-inflammatory, and vicodin for = pain. since I've been on the Mirapex (last 4 weeks), the Sinemet CR is = much more effective, but both my hands have been swollen and either numb = or VERY painful for the past 3 weeks. Does anyone know if this could be = due to the medication? I hate to go back to the off/on I had without = the Mirapex, but I have to get my hands to "unswell". Ice, heat, = e-stim, or ultrasound have not worked. Any ideas? Please? Bob ------=_NextPart_000_0212_01BE3B49.799C7260 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable <!DOCTYPE HTML PUBLIC "-//W3C//DTD W3 HTML//EN"> <HTML> <HEAD> <META content=3Dtext/html;charset=3Diso-8859-1 = http-equiv=3DContent-Type> <META content=3D'"MSHTML 4.72.3110.7"' name=3DGENERATOR> </HEAD> <BODY bgColor=3D#ffffff> <DIV><FONT color=3D#000000 size=3D2>I am taking Sinemet, Sinemet CR, = Mirapex,=20 clonzepam, and amitriptyline for my PD. I also take Ultram for an=20 anti-inflammatory, and vicodin for pain. since I've been on the = Mirapex=20 (last 4 weeks), the Sinemet CR is much more effective, but both my hands = have=20 been swollen and either numb or VERY painful for the past 3 weeks. = Does=20 anyone know if this could be due to the medication? I hate to go = back to=20 the off/on I had without the Mirapex, but I have to get my hands to=20 "unswell". Ice, heat, e-stim, or ultrasound have not=20 worked. Any ideas? Please?</FONT></DIV> <DIV><FONT color=3D#000000 size=3D2>Bob</FONT></DIV></BODY></HTML> ------=_NextPart_000_0212_01BE3B49.799C7260--