My husband Ron, is experiencing more OFF or "down" time recently. For periods of 1 1/2 to 2 hours he says he feels paralysed and has what he describes as a steel band below his chest. He has great difficulty breathing in this state and speech is almost impossible as he says he has no strength. We question is it "just" Parkinsons or effects of medications. He takes Sinimet CR (50/200)totalling 1600 to 1800 mg. per 24 hours.He was diagnosed in 1989. We wonder if others experience anything similar when OFF. Weight loss has been considerable since onset of described conditions. Any help, suggestions would be most appreciated. Thank you, Maureen for Ron.67.