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On Thu 14 Jan, Callie M. Judd wrote: > Maureen: Thought I'd share my husband's exp. since he's 69 and has had it l2 > yr. > His regimen involves presently, 600mg/day Sinimet Cr&l00st mixed > l mg/day Cogentin ( > something few have mentioned but has always helped the tremors ) > l5 mg. Bromocriptine ( > recently added as an > agonist- taking it slow - seems to be helping some) > I have a question to you- Why so much Sinimet? The most we've taken(my > husband asks when I'm going to start my doses, har,har) is l000mg/day and > work to minimize it. When he feels overdosed, there seems to be more > difficulties > symptomatic to PD. Sometimes we miss doses and seems to be better - but know > we can't go to long with too little, but some variances help I think. > Also, has he had a thyroid checkup for the possibilities of weight loss? > Let me know, he's the first I've heard of on such high levels of Sinimet.... > > Blessed to be with you all... > > Marie > > > Hello Marie, You ask why your huband takes as much as 600 mg/day of Sinemet. Well, the fact is, 600mg is actually lower than average, for person who has 12 yrs under his belt. I think that you may have been misled by the low intake of people who are relative newcomers to PD. The diversity of people and dosages can be very confusing. I would say that 800 to 900 mg /day of Sinemet is a fairly typical value. but of course individuals vary quite substatially from this average value. Regards -- Brian Collins <[log in to unmask]> 59yrs diagnosed 39 First symptoms 33