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Gisela Steinert gave the list information from attending a symposium in Germany. It was the opinion of Prof. Dr. Moussa B.H. Youdim from Haifa who said in part: ---------- > > Of the drugs examined, we have shown that apomorphine (a drug first > synthesized in Germany 135years ego) , the antiparkinson dopamine DI-D2 > receptor agonist, is one of > most potent iron chelators so far described. Apomorphine protects dopamine > neurons death as induced by neurotoxins (MPTP, 6-hydoxydopamine and iron) in > vitro, in vivo and in cell culture experiments. We know of no other presently > available anti PD drug which has the neuroprotective actions of apomorphine in > animal models of PD. Thus apomorphine may be the most ideal drug available for > clinical neuroprotection. Recent long term clinical studies in Europe with > apomorphine is showing remarkable action, namely that long term parkinsonian > apomorphine users are stabilized and can be weaned of L-dopa. The question to > be investigated is whether in such patients apomorphine is showing > europrotection and slowing the progression of the disease. This is now been > investigated clinically by our group in collaboration with Prof. Poewe > (Austria) and Prf Leenders (Holland) using PET and SPECT. My questions to the list are: Is apomorphine being used in the USA at present as a drug for Parkinson's? By what name(s) is it called? Have any list members used this drug successfully? Jeanette Fuhr 48/47/44?