1. Has anyone had a bad reaction to Requip? I started on it, slowly, a month ago. I went t the full I mg dose three times a day from 3/4 mg 5 days ago. The day before yesterday my voice, which has been one of my biggest problems for a couple of years, suddenly got much worse - to the point where I am suddenly virtually unintelligible. Besides the dramatic change in my voice, I just feel out of sorts, kind of a sick feeling, although not at all dramatic. I have to say that I may have one of the PD+ diseases so none of you might be able to relate to my situation. A test in December eliminated PSP, Progressive Supranuclear Palsy, as a suspect but there are other candidates. None of the drugs work for me. I have tried Permax, Mirapex, Tasmar and now Requip. None has helped my inability to walk unaided and my terrible gait; my serious speech problem (I had Lee Silverman therapy about 9 months ago - it seemed to help at first but it's been downhill all the way for me up to this latest episode), my poor posture & back ache, as well as my now near blindness much of the time from blephrospasnm in both eyes. I don't have ON's & OFF's & no tremors. I do have some of the other PD symptoms, though. I am probably grasping at straws in hoping this is a reaction to Requip, but not being able to be understood at all now is very distressing - as is the possibility I don't even belong here with you folks [distressing to me anyway] 2. I am having an MRI on Tuesday. Like a dummy I didn't even ask my doctor what this is supposed to tell him. The prescription form says Rx MRI of the brain, without gadolinium, Dx atypical Parkinson;s Disease. Does anyone know if this will be at all definitive as to what I have? THANKS TO ANYONE WHO CAN SHED ANY LIGHT ON THESE 2 THINGS FOR ME!! B. Bruce Anderson (53, 5) Schooley's Mtn., NJ [log in to unmask]