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Bob, I too have been taking Mirapex. I am on my fifth week and tomorrow start on.75 mg and the 6th week will be topping out at 1.5 mg. Have not noticed any side affects yet although I think I am a rare case being I haven't taken any drugs previously. I'm following the list for Mirapex reports and would appreciate any informationyou have in the future. Best wishes to Cecily PS --I haven't noticed any benefits from the drug yet. [log in to unmask] Message----- From: Bob Anibal <[log in to unmask]> To: Multiple recipients of list PARKINSN <[log in to unmask]> Date: Sunday, January 24, 1999 5:23 AM Subject: Re: Requip reaction/ MRI >Some months ago Cecily had been put on Requip. she never reached the full >dosage as she got tummy aches. She is now titrating up on Mirapex, but I am >having some doubts as to its ability to substitute 100% for Sinemet. She got >up to .5mg at 6am .5mg at noon and .375mg at 6-8pm + 1/2 of a 25/100 >sinemet. The previous week had been .375+ 1/2 sinemet at noon. The second >day of the new regimen she froze more than previous week. After 2 days of >this I went back to the previous regimen. Now she is taking .375mg Mirapex >3X and 1/2 25/100 sinemet 3x. >Has anyone else seen any similar effects from Mirapex. >Bob Anibal CG for Cecily 78/20