Pharmaceutical companies that produce anti-parkinsonian medications are all based on the Sinemet model. Several tablets per day titrated. The more tablets you require, the more revenue. Given the cost of bringing a compound to market which is 200 to 300 million US dollars, a $50 or $500 dollar shot doesn't make much business sense. National Parkinson's organizations derive a good portion of their revenues from drug companies sponsorship of clinical trials and seminars and patient materials. They are interested in getting the most portion of any government research. Patients are easily motivated in helping the organizations reach their goals through lobbying Congress for increases in funding. Ideas such as using neutered viruses that will pass the blood-brain barrier have seemed feasible for several years as a way to get things such as missing chemicals or compounds into the brain. Startup companies generally come forward with the best new science...but it takes two to tango. Most high-tech neuro-biological enterprises are leveraged to the hilt and have balance sheets in the red...especially if a company with deep pockets does not buy their technology and research. It is in the World interest to cure Parkinson's but it doesn't make much sense to those who are deriving their revenues "treating" Parkinson's. The surgical techniques and the implant procedures are experimental at best and do not stop the progression but merely slow it in the best cases. Government funding and with that "openness" of information is the only way Parkinson's and other neurological disorders are going to be cured. Finding a cure for Parkinson's should not be dependent on free enterprise. [log in to unmask] Search the parkinsn archive online at: http://james.parkinsons.org.uk Catch the Parkinsn List messages on line at: http://www.ionet.net/~jcott/homepage/archive/patp.html *NEW*Click the page ads and use the new search tools*NEW* John Cottingham