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Hi David: My husband, Dan 50 diagnosed last spring.....sounded much like you. He had the shuffle in his gait, affecting the left side....dexterity problems like difficulty brushing his teeth, buttoning his shirt, handwriting problems and the SHOULDER....frozen painfully in an upright position. This was my husband's most difficult symptom to deal with, too. We went to several different doctors and finally decided to go with the Miapex and Eldepryl. We couldn't be happier with the results! He has no side effects, no noticable symptoms as long as he takes his medication on time . THE SHOULDER HAS NOT BEEN A PROBLEM SINCE.....And his whole personality has changed from depression back to the man he was over 10 years ago. You, too, will have to make your own choices, but we chose NOT to start the sinimet until the dopamine agonists no longer give him symptomatic relief because of all the research we have studied. (This is OUR opinion, but if you are looking for opinions......) I just read your letter to my husband and he says you sound just like he used to.....and he is so thankful for the medications!! Good luck with your choices...... Juelie McLean CG Dan 50 / dx 98