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Mark Steiner wrote: > > I AM CURRENTLY TAKING THE FOLLOWING COCKTAIL DAILY; > SINEMET, PERMAX, TASMAR, ADIVAN, AND, MOST RECENTLY ADDED, TRAZIDONE. I TOOK, > PER DOCTOR, TWO TRAZIDONE, ONE MORE THAN THE PREVIOUS NIGHT, AND WOKE UP ABOUT > 2 AM IN A STATE OF SEMI-PARALYSIS, GREAT BREATHING DIFFICULTY. (NOTE; I AM 51, > BEEN DIAGNOSED FOR 19 YEARS!) > ANYONE AWARE OF ADVERSE REACTIONS BETWEEN THESE PARTICULAR DRUGS? > THANX FRIENDS, MARK Mark, Here is some information I've located -- you might want to discuss with your physician your breathing difficulty and ask if a medication might have contributed to this condition. Possible adverse reactions: dyspnea (pergolide) --this means breathing difficulty, shortness of breath respiratory depression (lorazepam/Ativan) sedation (tolcapone) weakness (pergolide) ========== Concomitant administration of lorazepam/Ativan with CNS-depressant drugs (Trazodone), can potentiate the CNS effects (i.e., increased sedation or respiratory depression) of either agent. My very best regards, Kathrynne -- Kathrynne Holden, MS, RD "Nutrition you can live with!" Medical nutrition therapy http://www.nutritionucanlivewith.com/ Tel: 970-493-6532 // Fax: 970-493-6538 "If we knew what it was we were doing, it would not be called research, would it?" -Albert Einstein