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Jo, What I meant to say was that I take my meds shortly before I exercise so that they will hopefully kick in around the time that I start exercising; and that often involves overlapping an ongoing "on" period, which on second thought is probably what Joe B. meant by "accelerating" doses. I hope this is helpful. By the way, I also find that I have to be careful not to 'wait too long before I exercise to take the meds because if I do, the meds won't kick in while I'm exercising' Marty