All of these meds sedating. You did not mention the mg dose of the trazodone tablets. Trazodone is an extremely sedating antidepressant that it is my guess- could be the straw that broke the camels back. It is often prescribed for sleep because it is so sedating. I certainly have seen patients who have had "strange" reactions to it. Definitely you should check with your doctor. Charlie Mark Steiner wrote: > here is my revised(with dosages) message; > i take the following cocktail; > sinemet 25/100, 6 day, cr50/200, 1 0r 2/night > permax 1 mg 8x day > ADIVAN 1 mg 3x day > TASMAR 100 mg 3x day > latest addition; TRAZIDONE (?)1-4 night > i took 3 TRAZIDONE (1, followed b 2, later) and had severe reaction. > comments? > thanx, mark -- ****************************************************************************************** Charles T. Meyer, M.D. Middleton (Madison), Wisconsin [log in to unmask] ******************************************************************************************