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Marty Polonski and Will Johnnston seem to agree with Joe Bruman's theory and advice to William A. Parrette that exercise will "use up" available dopamine and that it would not be harmful to take a little additional dopamine to offset the loss. I beg to differ. In my experience, not only exercise will cause an increase of tremor, but any kind of stress, or exitement, like getting up in a crowd and speaking, will do that. I would say, any cause that may increase the release of adrenalyn in the bloodstream will have that effect. Stopping the exercise or taking away the other causes is enough for the tremor to subside. I don't think the dopamine is "used up"; it is just otherwise occupied. I don't see that taking extra dopamine will help much, because of the time it needs to take effect. A good example is when I try to turn around in bed. The effort causes a sudden flare-up of tremor which stops as soon as I quit struggling. Supposedly,according to the theory that is the time when there should be some dopamine in reserve! Not that I can notice! It would be interesting to investigate the interplay of adrenalyn and dopamine under controlled conditions. Will A. Kuipers Dallas, Texas 78 / 71 / 70 <[log in to unmask]>