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Will A. Kuipers wrote: > > Marty Polonski and Will Johnnston seem to agree with Joe Bruman's theory and > advice to William A. Parrette that exercise will "use up" available dopamine > and that it would not be harmful to take a little additional dopamine to > offset the loss. > I beg to differ. > In my experience, not only exercise will cause an increase of tremor, but > any kind of stress, or exitement, like getting up in a crowd and speaking, > will do that. My problem with exertion is not the tremor, which is only a minor and tolerable end-of-dose effect, but pseudo-fatigue, or what I choose to call reversible PD-related exhaustion. The signs are just like those of the real thing, including raised pulse and breathing rate, and aching muscles, but also intense pain (which I infer is from dystonia) in remote muscles having no part in the exertion. All this vanishes a few minutes after a Sinemet pill. All I can say is, it works for me. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013