Hello Brian and Bernard,
My experience of Madopar is somewhat
different to that expressed by Brian, I have been taking it for ten years now
and have always been prepared to try to "fine tune" the times I take it and
dosage amount in order to achieve what I consider to be the optimum benefit. I
presently take 187.5 mg 3 times a day at 4 hourly intervals, starting at 8.30
am.which involves an "on" period followed by an "off" period before taking the
next dose.
I suppose it depends on how severe your "off" periods are, but when I tried the
overlap method of dosage, I found that I was taking 4 doses of Madopar per day
instead of 3, resulting in increased dyskenesia and shorter "on" times.As I am
still quite mobile during my "off" times, I find it preferable to use this
method of Madopar control.
As a follow- on to the above comments, since I have been taking Cabaser { 15
months now} the dreaded Dyskenesia which used to blight my life has 99%
disappeared!
Regards,
Nigel,
Brian Collins wrote:
> On Tue 09 Feb, bernard.shaw wrote:
> > A big hello to all fellow PWPs. I went to see my Neuro two weeks ago and
> > asked him to change me from Sinamet cr 250mgs back on to Madopar. 4x 125
> > mgs. per diem. The madopar is water soluable and I have no difficulties in
> > swallowing. My aches and pains are less but the tremor is a little more
> > pronounced. I feel much better with Madopar and my off periods are not so
> > long. Bern from Austria.
> >
> > http://members.teleweb.at/bernard.shaw/Poetry.txt
> >
> >
> >
> Hello Bernard, that looks like a really good change, and you are nicely
> poised to take a further step forward, if you wish to get rid of that
> remaining tremor.
>
> Also, you refer to your off periods being not so long. How long are the
> offs? There really is no need to tolerate off periods, when all you have
> to do is bring the next tablet forward slightly so that the two tablets
> overlap by ,say, 15 to 20 minutes.
> I really believe that it puts less strain on your dopamine system if
> you schedule your tablets so that you run at a fairly constant level,
> rather than cycle from on to off and to on again between each tablet.
>
> Regards,
> --
> Brian Collins <[log in to unmask]>
