Hi,
Can you tell me how and if Cabaser and Madopar are available in the U.S. ?
Many of my PD friends suffer from these off periods and dyskenesias, and
eventually so will I. I'm not "hip" on how to get drugs from nontraditional
means in the U.S.
Ann
________________
Nigel Harland wrote:
>
> Hello Brian and Bernard,
> My experience of Madopar is somewhat
> different to that expressed by Brian, I have been taking it for ten years now
> and have always been prepared to try to "fine tune" the times I take it and
> dosage amount in order to achieve what I consider to be the optimum benefit. I
> presently take 187.5 mg 3 times a day at 4 hourly intervals, starting at 8.30
> am.which involves an "on" period followed by an "off" period before taking the
> next dose.
> I suppose it depends on how severe your "off" periods are, but when I tried the
> overlap method of dosage, I found that I was taking 4 doses of Madopar per day
> instead of 3, resulting in increased dyskenesia and shorter "on" times.As I am
> still quite mobile during my "off" times, I find it preferable to use this
> method of Madopar control.
> As a follow- on to the above comments, since I have been taking Cabaser { 15
> months now} the dreaded Dyskenesia which used to blight my life has 99%
> disappeared!
> Regards,
> Nigel,
>
> Brian Collins wrote:
>
> > On Tue 09 Feb, bernard.shaw wrote:
> > > A big hello to all fellow PWPs. I went to see my Neuro two weeks ago and
> > > asked him to change me from Sinamet cr 250mgs back on to Madopar. 4x 125
> > > mgs. per diem. The madopar is water soluable and I have no difficulties in
> > > swallowing. My aches and pains are less but the tremor is a little more
> > > pronounced. I feel much better with Madopar and my off periods are not so
> > > long. Bern from Austria.
> > >
> > > http://members.teleweb.at/bernard.shaw/Poetry.txt
> > >
> > >
> > >
> > Hello Bernard, that looks like a really good change, and you are nicely
> > poised to take a further step forward, if you wish to get rid of that
> > remaining tremor.
> >
> > Also, you refer to your off periods being not so long. How long are the
> > offs? There really is no need to tolerate off periods, when all you have
> > to do is bring the next tablet forward slightly so that the two tablets
> > overlap by ,say, 15 to 20 minutes.
> > I really believe that it puts less strain on your dopamine system if
> > you schedule your tablets so that you run at a fairly constant level,
> > rather than cycle from on to off and to on again between each tablet.
> >
> > Regards,
> > --
> > Brian Collins <[log in to unmask]>
