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Hi Brian , I have some questions : Brian Collins wrote: > I have always felt a little sensitive about the fact that my Model > defines dyskinesia as being the result of the Dopamine level exceeding > a critical value, and perhaps getting to synapses which were not the > original target, thus sending the electrical message to the wrong muscles. > > My point is that I can produce plausible explanations for most of the > phenomena which we associate with dyskinesias (including the dreaded > Di-phasic Dyskinesia) How to explain the fact that in SOME well done Pallidoctomy (destrying some brain cells and neurons) there happens a elimination of the tremors and a reduction or even the elimination of the need of taking levodopa ?? > I am beginning to wonder..... You know the old saying: > > If it looks like a duck, walks like a duck, quacks like as duck, > and lays eggs, then maybe, just maybe, it IS a duck. BTW do you know what looks like a lion, walks like a lion, roars like a lion and does not lay eggs like a lion , but is NOT a lion ?? :-) Cheers, -- +----| Joao Paulo de Carvalho |------ + | [log in to unmask] | +--------| Salvador-Bahia-Brazil |------+