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Dear Sherilyn, Nausea is very common in the beginning of Sinemet use; however, your physician can prescribe Lodosyn to help. I'm not sure about the migraine, but I would certainly discuss this with your neurologist. My very best regards, Kathrynne Sherilyn Sherry wrote: > > This morning I took my first SInemet CR 50/200 at about 9 with > breakfast. At 11:30 I became extremely nauseaus and had to go to bed > not being able to move a muscle without feelling like I was going to > throw up. Later I developoed a Migraine. Now I'm afraid to take > another Sinemet. Could the Sinemet have caused my problems or was it a > coincidence? -- Kathrynne Holden, MS, RD "Nutrition you can live with!" Medical nutrition therapy http://www.nutritionucanlivewith.com/ Tel: 970-493-6532 // Fax: 970-493-6538 "If we knew what it was we were doing, it would not be called research, would it?" -Albert Einstein