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I have just seen the Physician's Desk Reference for 1999. FYI, the entry for tolcapone (Tasmar) reflects the original package insert, and lacks the boxed WARNING and stricter recommended liver function monitoring of the revised package insert issued in November 1998. Cheers, Joe -- J. R. Bruman (818) 789-3694 3527 Cody Road Sherman Oaks, CA 91403-5013