Peter, I do take Eldepryl (5mg twice/day) and have never been told that Alleve/Naprosin did not mix with it. I have never noticed any problems when I take them both. I have found with back pain as well as other points of orthopedic pain, that the "PD devil" loves to tweak those tender spots by locking up the muscle or sending little waves of spasms. I have a hand electric massager which looks like a flash light w/ an over-sized hockey puck on one end! The hockey puck vibrates like an oscillating sander, and its curved outer surface lets you really bear down on those tight, tense, tired muscles. take care, Steve 52/16