Hello David, this was the very first symptom I had. Madopar works very well against this. (For me at least!) Is Muriel taking any medications? /John. On Fri, 5 Mar 1999, David Silverman wrote: > I am a caregiver for my dear friend (66/4) Muriel. She has been > diagnosed with Parkinsonism (possibly striatonigral degneration). Lately > she has been much troubled with her fingers closing on her hand so that > she has a fist instead of an operating hand. This makes it difficult to > hold anything. When she tries to pry open her fingers she has > considerable pain and difficulty.She is wondering whether the problem is > arthritis or a Parkinson problem. Does anyone have any knowledge or > experience with this problem. Any information would be greatly > appreciated. Thank you for your thoughts. David Silverman >