The Autumn 1998 issue of the NPF Parkinson Report has an article on Mitochondrial COQ-10.They describe on-going studies evaluating benefits to PD patients;so far unproven. Potential benefits are based on COQ-10's dual roles in mitochondrial function and as an anti-oxidant since PD patients have both mitochondrial dysfunction and damage to nerve cells in the substantia nigra due to oxidative free radicals. I have a file entitled: INTRODUCTION TO COENZYME Q10 By PETER H. LANGSJOEN, M.D., F.A.C.C. which I can send to anyone interested.Since it is longer than 500 lines it can't be sent on this list.Benefits are cited for people with heart disease. Gil,CG for Aliza ------------------------------ Date: Sun, 7 Mar 1999 06:53:41 -0600 From: Linda Potter <[log in to unmask]> Subject: Re: Coenzyme Q-ten? On Sat, 6 Mar 1999 20:42:57 EST John Gooch <[log in to unmask]> writes: >Does anyone want to say anything or any praises for this? >I am still trying to find out what it is and how it works for PD. > John - Of course I can't find my reference on coenzyme Q10 now, but basically it is an antioxidant which is supposed to rid the body ( brain ) of free radicals , which destroy our dopamine source, the substantia nigra. I hope I got it right. Linda ----------- Date: Sun, 7 Mar 1999 09:18:09 -0500 From: MR JOSEPH GIBBONS <[log in to unmask]> Subject: co-enzyme Q-10 John--Look in the archives for 1/21/99. There will be a 3-year study to determine if Co-enzyme Q-10 is neuroprotective. Dosages will be 300, 600, or 1,200 milligrams per day. The archive address is http://james.parkinsons.org.uk/index.htm. Ann Gibbons ------------------------------