Dear Billie,
Is the same doctor prescribing all these drugs, or are different doctors
prescribing them? Sometimes when more than one doctor is involved, they
don't all know what the others are prescribing, and though each is
carefully monitoring the drugs s/he has prescribed, they are unaware of
the other medications the individual is using.
There are many possible drug interactions on this list, and also many
possible additive adverse effects. You mention staggering and falling --
this could be due to orthostatic hypotension. The following could cause
this: bromocriptine; doxepin; fluoxetine; furosemide;
levodopa/carbidopa; promethazine; selegiline.
It could also be due to loss of electrolytes from the lasix you're
taking. Lasix is a powerful diuretic, and it causes loss of potassium,
among other things, which could be part of your problem.
You're taking a lot of drugs that can cause nausea:
acetaminophen (Darvocet); bromocriptine (Parlodel); doxepin; fluoxetine
(Prozac); furosemide (lasix); levodopa/carbidopa; metoprolol
(Lopressor); selegiline; verapamil (Calan).
Both doxepin and Prozac can lead to tremor.
Phenergan and doxepin can cause parkinson-type symptoms.
You sudden loss of 30 pounds may very well mean a loss of vital
nutrients; you report a sore tongue, which can result from B vitamin
deficiency, and this can occur with sudden weight loss, particularly as
you say you're not eating -- you're probably getting enough vitamins to
prevent malnutrition.
The phenergan has sedative effects and could contribute to your
staggering and falling. It also increases your need for the B vitamin
riboflavin. Signs of riboflavin deficiency include sore tongue, as you
report. Finally, it can contribute to loss of taste, another problem you
report. Could your physician prescribe lodosyn for the nausea? Lodosyn
is recommended for nausea in "Algorithm for Management of Parkinson's
Disease" by Olanow and Koller.
Phenergan can also diminish the effects of Sinemet and bromocriptine.
There are also possible adverse interactions between Prozac and doxepin,
and between Eldepryl and Doxepin.
Side effects can result from the combination of Eldepryl and Prozac.
Parlodel and lasix in combination can lead to hypotension, as can
levodopa and lasix, and lopressor and lasix.
I'm sure your doctor or doctors are carefully monitoring the dosages of
these medications, but you should immediately report your feelings to
your doctor or doctors. If more than one doctor, be sure all of them
know about every one of these drugs. It's possible that the drugs
themselves are part of your problem, and your doctor needs to know your
experiences as soon as possible, particularly in view of your falling,
weight loss, sore tongue and nausea.
You should also ask for a referral to a registered dietitian, preferably
one who is experienced with PD, for help with the weight loss and
possible malnutrition.
My very best regards,
Kathrynne
Billie Cook wrote:
> Have had a sore mouth for quite some time now and they don't know how
> comd.At any rate because of a sore tongue which burns and stings when I
> eat or drink and the fact that nothing has any taste I'm not eating and
> have lost about 30 lbs in 5/6 weeks.
> Does anybody have any words of widsom for me? they would be appreciated.
> Outside of falling ,staggering,shaking,and problems getting up and down
> guess I'm doing fine.
--
Kathrynne Holden, MS, RD
Medical nutrition therapy
http://www.nutritionucanlivewith.com/
"We are living in a world today where
lemonade is made from artificial flavors and
furniture polish is made from real lemons." --Alfred E. Newman
