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Dear Laurie: My mother has periods of feeling extremely hot with extreme rigidity. This usually occurs between 7-8pm but can occur at any time. My mother will take her dissolved Sinemet at 5 pm and then eat her 1 cup of rice with veggies at 5:15 or 5:30 (after the Sinemet has taken effect). If her meal was even just a little more than usual, the residual food in her stomach (or small intestine) interferes with her 7pm dosage. That is when the hot spells really hit hard. Reducing her protein intake has, also, helped reduce these hot spells. My father will, occasionally, lightly press a cool wet cloth against her skin. It really doesn't help much but for my mother it gives her the sense that something is being done to help. As for the panicky feeling, those episodes eventually went away. My father suggests maybe Xanax to help with the panic. Teresa